S@feMate Cyto
Total Safety Protection for Cytotoxic Drug Handling

The S@feMate Cyto is a state of the art Class 2 Microbiological Safety Cabinet specifically designed to provide a safe working environment for handling cytotoxic drugs (sometimes known as antineoplastics).

The S@feMate Cyto Class 2 Safety Cabinet provides class leading operator and environmental protection, whilst also providing safety for the product by maintaining a Class 100 / ISO Class 5 working environment.

  • Triple filter design with one supply downflow filter and two exhaust filters.
  • State of the art microprocessor control system.
  • Air and aerosol tight electrical sliding sash system.
  • Patented Bag-in / Bag-out filter replacement system.
  • Certified in accordance with DIN 12980:2005 and EN 12469:2000.
Safety for the Operator and the Environment

Operator protection is obtained thanks to the excellent containment efficiency of the front air barrier and the double filtration of the air discharged in the environment.

The S@feMate Cyto Microbiological Safety Cabinet has three HEPA H14 filters:

  • A primary exhaust filter below the work surface to ensure particulate contamination is collected at source keeping the cabinet’s air paths clean.
  • A downflow filter to provide ISO 5 / Class 100 air cleanliness to the working zone.
  • A second stage exhaust filter to ensure environmental protection is guaranteed.
Safety for the Product and the Patient

The sterility of the drugs is essential for the safety of the product and patient receiving the prepared drugs. The S@feMate Cyto provides ISO 5 / Class 100 air cleanliness inside the cabinet work area.

Safety for the Maintenance Engineer

Replacement of the primary exhaust HEPA filter (located under the work surface) is made safe thanks to a patented “bag-in/bag-out” system. This system enables changing of the filter without any risk of exposure to dangerous compounds for both the engineer and local environment.

The downflow and exhaust HEPA filters further process the air passing through the primary filter.

The HEPA filtered downflow air within the work chamber exceeds the required cleanliness class of ISO 5 (equivalent to Class 100) for the preparation of paranteral drugs. All recirculated air passes through at least 2 HEPA filters prior to exhaust to ensure safety of the local environment.

Technical Features:
  • Four levels of safety are provided
    1. Safety for the operator: high aperture protection factor, identical to that of a Biological Safety Cabinet.
    2. Safety for the environment: (two stage H14 HEPA filtration for all exhausted air).
    3. Safety for the product and between products: exceeds ISO 5, GMP Grade A and class 100 in the work area.
    4. Safety for the maintenance engineers: ‘bag in bag out’ procedure when changing the primary filter.
  • Microprocessor controlled motor blower, with volumetric sensor for exhaust air flow monitoring
  • State of the art Microprocessor control system offering:
    • Automatic control of preset airflow volumes
    • Sliding sash window with smart control
    • Permanent monitoring of HEPA filter life span
    • Multilevel alarms, with redundancy functions
    • Permanent display of cabinet condition
    • Highest air flow stability both in case of transitional disturbances or to progressive filter clogging
    • Semi-automatic fumigation cycle (EN 12297 tested and certified)
    • Continuous monitoring of front barrier air flow for the highest operator safety
    • Low barrier alarm
    • Power failure alarm
  • Volt-free contact for remote monitoring of exhaust fan
  • Automatic reset of initial conditions in case of power failure
  • Comfortable front opening height of 200mm
  • Cytotoxic drugs handling
  • Manipulations of microorganisms, bacteria, fungi, virus and parasite risk groups 1, 2 and 3
  • Isolation and culture of samples
  • Quantification methods
  • Microscopy techniques and sample preparation
  • Identification and typing of microorganisms
  • Genetic manipulation
S@feMate Cyto Drugs Handling Cabinet Range:

S@femate Cyto 0.9

S@femate Cyto 1.2

S@femate Cyto 1.8

Dimensions of Work Chamber:
(W x D x H) mm

924 x 600 x 700

1230 x 600 x 700

1830 x 600 x 700

Overall Dimensions:
(W x D x H) mm

1074 x 840 x 2220

1380 x 840 x 2220

1990 x 840 x 2220

Height on Stand: (mm)




Front Opening Height: (mm)




Air Filter Grade:

H14 class HEPA filters with 99.999% efficiency at 0.3 micron particle size
(most penetrating particle size). EN1822-1 and EN 13091:1999 tested and certified


310 kgs

340 kgs

450 kgs

Electrical Supply:




Noise Level:

< 55 dB (A)

< 55 dB (A)

< 55 dB (A)

Lighting Level:

> 1200 lux

> 1200 lux

> 1200 lux

Optional Items:

LCD Monitor

Mobile UV Lamp